Diffusion‐weighted MRI  in patients with acute stroke 

  • Sahar Basim Ahmed Department of Radiology, AlYarmouk teaching hospital, Baghdad, Iraq.
  • Akram M. Al-Mahdawi Department of Radiology, AlYarmouk teaching hospital, Baghdad, Iraq.
  • Nosseba H. Department of Radiology, AlYarmouk teaching hospital, Baghdad, Iraq.


Background: Acute stroke is an abrupt non‐traumatic brain insult, caused by  either brain infarction (75%) or hemorrhage (25%). Aim of the Study: To compare the sensitivity of Diffusion ‐ weighted imaging  (DWI) and apparent diffusion coefficient (ADC) map in detection of acute  stroke with sensitivity of conventional MRI study. Patients &methods: Thirty ‐ eight    patients (24 male and 14 female with age  range between 43‐90 years) with a clinically suggestive stroke and negative  CT‐scan, all patients referred for MRI study within 4‐40 hours [mean of 17 hrs]  of acute attack. brain MRI was performed for these patients. Starting  with  conventional MRI  sequences done followed by diffusion weighted  in the  same study and  follow up clinically afterwards. The study was conducted in  a general hospital in Baghdad from January 2012 to January  2013 .Ratios were  calculated  between  the  apparent  diffusion  coefficient  value  of  normal  appearing brain in the right & left hemispheres & between apparent diffusion  coefficient  value of the ischemic area & the corresponding contralateral  region . Results:   With diffusion ‐ weighted images  , 100%  of the ischemic lesions  were detected, and with fluid‐attenuated inversion recovery, 73.7% were  detected, whereas with early T2‐weighted or T1‐weighted, only  52.6 %  and    21%  of lesions were detected , respectively , using McNemar test we found  statistically significant differences in sensitivity between Diffusion weighted  images  and T1W (p<o.ooo1), diffusion weighted images  and T2W (p<0.0001)  and between diffusion weighted images  and fluid attenuated inversion  recovery  (p< 0.002) .The mean apparent diffusion coefficient  of acute  ischemic lesions was 30 % lower than the apparent diffusion coefficient of  normal appearing parts of brain .( P <0.001).   Conclusions: Diffusion ‐Weighted images  + apparent diffusion coefficient   map Imaging is more sensitive than conventional MRI sequences in MRI  detection of acute stroke .  

How to Cite
AHMED, Sahar Basim; AL-MAHDAWI, Akram M.; H., Nosseba. Diffusion‐weighted MRI  in patients with acute stroke . Mustansiriya Medical Journal, [S.l.], v. 13, n. 2, p. 5, june 2018. ISSN 2227-4081. Available at: <http://mmj.uomustansiriyah.edu.iq/index.php/MMJ/article/view/208>. Date accessed: 10 apr. 2020.