Serum Level of Interleukin 6 & Tumor Necrosis Factor in Iraqi Breast Cancer patients

Abstract

Interleukin 6 (IL‐6) and tumor necrosis factor α (TNF‐α) may be used as a prognostic value in breast cancer .Serum levels of  IL‐6 , TNF ‐ α were elevated significantly, among the 40 sera samples of female breast cancer patients compared to the 20 healthy control samples (P<0.05).

 The level of IL‐6 and TNF‐α were significantly higher in metastasis breast cancer patients than those with local site (P<0.05), Furthermore, these results showed a positive correlation between IL‐6 and TNF ‐ α levels; the coefficient of correlation (r) was 0.98 which was statistically significant (P<0.05). These results indicate that serum IL‐6 and TNF – α level may be used in the assessment of breast cancer patients.