A study of the correlation between the histopathological grading and size of breast cancer with the axillary lymph node involvement

Abstract

Background: breast cancer In  Iraq  is the  commonest  tumor  affecting females  accounting  for  more  than  18%  in 2007  of   registered  female cancers  with  increase incidence  in  young  women.

Aims: the  study  aims  to   outline    the    correlation  between  histopathological   grading  of  breast  cancer  cells  with    the ipsilateral A.L.N involvement in relation to the size of cancer.

Patients & methods: A continuous  prospective study where  by  almost  all  mastectomized  patient  for  breast cancer  in Al- Yarmouk Teaching Hospital were included  from  January 2008  to  January  2011, revision  to   all   histopathological    reports  in the histopathological  department was done , tables  were  made  and the P value was calculated.

Results: Breast cancer cases represent 28.1% of breast surgery  in   this Hospital during the period of study. The commonest age group was the 5th decade 36.9% followed by the 4th decade 23%. Urban cases more than rural area cases, (I.D.C) 81.5% and (I.L.C) 18.5%. Regarding The histological grading grade II came first 70.8% grade III 20% and grade (I) 9.2%, A.L.N involvement 100% in grade (III), 65.2%  In  grade (II) and  33.3%  in  grade I.   Breast cancer size 2-5 cm represent 63% of The cases, tumor size more than 5 cm represent 30% and those with size less than 2 cm 6.3%.

Conclusions: Breast cancer cases represent 28.1% of total breast surgical disease for the same period of time done in this hospital and this is an important percent which reflect the need for increased emphasis on early detection by clinical and mammographic method or U/S study.